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Covariables of Myocardial Function in Women and Men with Increased Body Mass Index.

ABSTRACT: INTRODUCTION:Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function assessed by global longitudinal strain (GLS) in these subjects. METHODS:493 subjects (mean age 47?±?9 years, 61% women) with BMI?>?27.0 kg/m2 and without known cardiac disease underwent 24-hour (24h) ambulatory blood pressure (BP) recording, body composition analysis, carotid-femoral pulse wave velocity (PWV) measurement and echocardiography. LV peak systolic GLS was measured by two-dimensional speckle tracking echocardiography and LV ejection fraction (EF) by biplane Simpson's method. Insulin sensitivity was assessed by homeostatic model of insulin resistance (HOMA-IR). RESULTS:Women had higher prevalence of increased waist circumference (99% vs. 82%), lower prevalence of hypertension (59 vs. 74%), and lower serum triglycerides (1.3?±?0.7 vs. 1.7?±?0.9 mmol/L) and carotid-femoral PWV (7.3?±?1.6 vs. 7.7?±?1.6 m/s) compared to men (all p?

SUBMITTER: Pristaj N 

PROVIDER: S-EPMC7661414 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Covariables of Myocardial Function in Women and Men with Increased Body Mass Index.

Pristaj Nadia N   Saeed Sahrai S   Midtbø Helga H   Halland Hilde H   Matre Knut K   Gerdts Eva E  

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 20201024 6

<h4>Introduction</h4>Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function assessed by global longitudinal strain (GLS) in these subjects.<h4>Methods</h4>493 subjects (mean age 47 ± 9 years, 61% women) with BMI > 27.0 kg/m<sup>2</sup> and without known cardiac disease underwent 24-hour (24h) ambulatory blood pressure (BP) recording, body compositi  ...[more]

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