Ontology highlight
ABSTRACT:
SUBMITTER: Perdiguero P
PROVIDER: S-EPMC7662092 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Perdiguero Pedro P Goméz-Esparza Maria C MC Martín Diana D Bird Steve S Soleto Irene I Morel Esther E Díaz-Rosales Patricia P Tafalla Carolina C
Frontiers in immunology 20201030
In mammals, Blimp1 (B lymphocyte-induced maturation protein 1) encoded by the <i>prdm1</i> gene and its homolog Hobit (homolog of Blimp1 in T cells) encoded by <i>znf683</i>, represent key transcriptional factors that control the development and differentiation of both B and T cells. Despite their essential role in the regulation of acquired immunity, this gene family has been largely unexplored in teleosts to date. Until now, one <i>prdm1</i> gene has been identified in most teleost species, wh ...[more]