Effect of Vitamin B12 Injection on the Vocal Performance of Professional Singers: A Randomized, Double-blind, Placebo-Controlled, Crossover Trial.

ABSTRACT:

Importance

One-third of singers and vocal professionals report experiencing a benefit from empirical vitamin B12 injections for improvement of mild singing-related symptoms (eg, reduced stamina, vocal fatigue, and effort). However, there is no objective evidence to support or refute these claims.

Objective

To assess the presence and magnitude of the effect of empirical vitamin B12 injection on the vocal performance of singers.

Design, setting, and participants

A randomized, double-blind, placebo-controlled, crossover trial was conducted from November 7, 2017, to November 30, 2018, at an academic voice center among 20 active adult singers without dysphonia but with mild vocal symptoms. Individuals with known or suspected vitamin B12 deficiency or active or recent vitam

SUBMITTER: Shoffel-Havakuk H 

PROVIDER: S-EPMC7662483 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature