Ontology highlight
ABSTRACT:
SUBMITTER: Righetti G
PROVIDER: S-EPMC7663332 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Righetti Giada G Casale Monica M Liessi Nara N Tasso Bruno B Salis Annalisa A Tonelli Michele M Millo Enrico E Pedemonte Nicoletta N Fossa Paola P Cichero Elena E
International journal of molecular sciences 20201029 21
Cystic fibrosis (CF) is the autosomal recessive disorder most recurrent in Caucasian populations. Different mutations involving the cystic fibrosis transmembrane regulator protein (CFTR) gene, which encodes the CFTR channel, are involved in CF. A number of life-prolonging therapies have been conceived and deeply investigated to combat this disease. Among them, the administration of the so-called CFTR modulators, such as correctors and potentiators, have led to quite beneficial effects. Recently, ...[more]