Ontology highlight
ABSTRACT:
SUBMITTER: Ould Amer Y
PROVIDER: S-EPMC7663848 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ould Amer Yasmine Y Hebert-Chatelain Etienne E
International journal of molecular sciences 20201105 21
Mitochondria are fully integrated in cell signaling. Reversible phosphorylation is involved in adjusting mitochondrial physiology to the cellular needs. Protein kinase A (PKA) phosphorylates several substrates present at the external surface of mitochondria to maintain cellular homeostasis. However, few targets of PKA located inside the organelle are known. The aim of this work was to characterize the impact and the interactome of PKA located inside mitochondria. Our results show that the overex ...[more]