Ontology highlight
ABSTRACT:
SUBMITTER: Feuillet V
PROVIDER: S-EPMC7664349 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Trends in immunology 20201113 1
The majority of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals remain paucisymptomatic, contrasting with a minority of infected individuals in danger of death. Here, we speculate that the robust disease resistance of most individuals is due to a swift production of type I interferon (IFNα/β), presumably sufficient to lower the viremia. A minority of infected individuals with a preexisting chronic inflammatory state fail to mount this early efficient response, l ...[more]