Ontology highlight
ABSTRACT:
SUBMITTER: Byrd AL
PROVIDER: S-EPMC7664509 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Byrd Allyson L AL Liu Menghan M Fujimura Kei E KE Lyalina Svetlana S Nagarkar Deepti R DR Charbit Bruno B Bergstedt Jacob J Patin Etienne E Harrison Oliver J OJ Quintana-Murci Lluís L Mellman Ira I Duffy Darragh D Albert Matthew L ML
The Journal of experimental medicine 20210101 1
As microbial therapeutics are increasingly being tested in diverse patient populations, it is essential to understand the host and environmental factors influencing the microbiome. Through analysis of 1,359 gut microbiome samples from 946 healthy donors of the Milieu Intérieur cohort, we detail how microbiome composition is associated with host factors, lifestyle parameters, and disease states. Using a genome-based taxonomy, we found biological sex was the strongest driver of community compositi ...[more]