Ontology highlight
ABSTRACT:
SUBMITTER: Komiya E
PROVIDER: S-EPMC7664892 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20201109 21
Itch (or pruritus) was not previously recognized as a serious symptom of psoriasis. However, approximately 60-90% of psoriatic patients with pruritus have stated that it deteriorates their quality of life. Since conventional antipruritic therapies, such as antihistamines, only exert limited effects, the establishment of a treatment option for itch in psoriasis is urgently needed. Although a definitive drug is not currently available, various itch mediators are known to be involved in pruritus in ...[more]