Ontology highlight
ABSTRACT:
SUBMITTER: Huang Y
PROVIDER: S-EPMC7667287 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Huang Ying Y Li Ruizhao R Zhang Li L Chen Yuanhan Y Dong Wei W Zhao Xingchen X Yang Huan H Zhang Shu S Xie Zhiyong Z Ye Zhiming Z Wang Weidong W Li Chunling C Li Zhilian Z Liu Shuangxin S Dong Zheng Z Yu Xueqing X Liang Xinling X
Frontiers in physiology 20201102
Diabetic kidney disease (DKD) is a serious and common complication of diabetes. Extracellular vesicles (EVs) have emerged as crucial vectors in cell-to-cell communication during the development of DKD. EVs may mediate intercellular communication between podocytes and proximal tubules. In this study, EVs were isolated from podocyte culture supernatants under high glucose (HG), normal glucose (NG), and iso-osmolality conditions, and then co-cultured with proximal tubular epithelial cells (PTECs). ...[more]