Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke.
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ABSTRACT: Background
We compared two simple and rapid diameter-based methods (ABC/2, od-value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml.Methods
In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od-value and ABC/2 calculation was compared to volumetric assessments.Results
Accuracy of od-value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity.Conclusions
Od-value is a robust tool for patient selection in trials.
SUBMITTER: Kufner A
PROVIDER: S-EPMC7667359 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke.
Kufner Anna A Stief Jonas J Siegerink Bob B Nolte Christian C Endres Matthias M Fiebach Jochen B JB
Brain and behavior 20200909 11
<h4>Background</h4>We compared two simple and rapid diameter-based methods (ABC/2, od-value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml.<h4>Methods</h4>In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od-value and ABC/2 calculation was compared to volumetric assessments.<h4>Results</h4>Accuracy of od-value and ABC/2 was simil ...[more]
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