Unknown

Dataset Information

0

Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke.


ABSTRACT: BACKGROUND:We compared two simple and rapid diameter-based methods (ABC/2, od-value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. METHODS:In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od-value and ABC/2 calculation was compared to volumetric assessments. RESULTS:Accuracy of od-value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity. CONCLUSIONS:Od-value is a robust tool for patient selection in trials.

SUBMITTER: Kufner A 

PROVIDER: S-EPMC7667359 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

altmetric image

Publications

Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke.

Kufner Anna A   Stief Jonas J   Siegerink Bob B   Nolte Christian C   Endres Matthias M   Fiebach Jochen B JB  

Brain and behavior 20200909 11


<h4>Background</h4>We compared two simple and rapid diameter-based methods (ABC/2, od-value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml.<h4>Methods</h4>In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od-value and ABC/2 calculation was compared to volumetric assessments.<h4>Results</h4>Accuracy of od-value and ABC/2 was simil  ...[more]

Similar Datasets

| S-EPMC9005571 | biostudies-literature
| S-EPMC4762011 | biostudies-literature
| S-EPMC5574871 | biostudies-literature
| S-EPMC10000880 | biostudies-literature
| S-EPMC8000439 | biostudies-literature
| S-EPMC2949206 | biostudies-literature
| S-EPMC7991428 | biostudies-literature
| S-EPMC8650827 | biostudies-literature
| S-EPMC3660654 | biostudies-literature
| S-EPMC3214028 | biostudies-literature