Ontology highlight
ABSTRACT:
SUBMITTER: Sajti E
PROVIDER: S-EPMC7667722 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Sajti Eniko E Link Verena M VM Ouyang Zhengyu Z Spann Nathanael J NJ Westin Emma E Romanoski Casey E CE Fonseca Gregory J GJ Prince Lawrence S LS Glass Christopher K CK
Nature immunology 20200120 2
The lung is inhabited by resident alveolar and interstitial macrophages as well as monocytic cells that survey lung tissues. Each cell type plays distinct functional roles under homeostatic and inflammatory conditions, but mechanisms establishing their molecular identities and functional potential remain poorly understood. In the present study, systematic evaluation of transcriptomes and open chromatin of alveolar macrophages (AMs), interstitial macrophages (IMs) and lung monocytes from two mous ...[more]