Young-Onset Colon Cancer and Recurrence Risk by Gene Expression.
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ABSTRACT:
SUBMITTER: Chang GJ
PROVIDER: S-EPMC7669228 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Young-Onset Colon Cancer and Recurrence Risk by Gene Expression.
Chang George J GJ You Y Nancy Y YNY Russell Christy A CA Tierno Marni B MB Turner Michelle M Bennett John P JP Lau Anna A Hochster Howard S HS
Journal of the National Cancer Institute 20201101 11
The incidence and mortality from colorectal cancer in younger adults (younger than 55 years) is increasing. We reviewed the complete database of a gene-expression test, Oncotype DX Colon Recurrence Score test, to determine age-related differences in recurrence score (RS) and single-gene results (7 cancer-related of the 12-gene assay). We included 20 478 stage II and III A and B colon cancer patients submitted to Genomic Health. RS results were grouped by low-, intermediate-, and high-risk groups ...[more]
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