Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC7669759 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhang Liwen L Ma Rong R Gao Mengcong M Zhao Yanyun Y Lv Xuemei X Zhu Wenjing W Han Li L Su Panpan P Fan Yue Y Yan Yuanyuan Y Zhao Lin L Ma Heyao H Wei Minjie M He Miao M
Frontiers in cell and developmental biology 20201103
Cancer stem cells (CSCs) are responsible for the migration and recurrence of cancer progression. Small nucleolar RNAs (snoRNAs) play important roles in tumor development. However, how snoRNAs contribute to the regulation of the stemness of ovarian CSCs (OCSCs) remains unclear. In the present study, we found that SNORA72 was significantly upregulated in OVCAR-3 spheroids (OS) and CAOV-3 spheroids (CS) with the OCSC characteristics attained by serum-free culture in a suspension of OVCAR-3 (OV) and ...[more]