Ontology highlight
ABSTRACT:
SUBMITTER: Brosens E
PROVIDER: S-EPMC7671559 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Brosens Erwin E Felix Janine F JF Boerema-de Munck Anne A de Jong Elisabeth M EM Lodder Elisabeth M EM Swagemakers Sigrid S Buscop-van Kempen Marjon M de Krijger Ronald R RR Wijnen Rene M H RMH van IJcken Wilfred F J WFJ van der Spek Peter P de Klein Annelies A Tibboel Dick D Rottier Robbert J RJ
PloS one 20201117 11
Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are relatively frequently occurring foregut malformations. EA/TEF is thought to have a strong genetic component. Not much is known regarding the biological processes disturbed or which cell type is affected in patients. This hampers the detection of the responsible culprits (genetic or environmental) for the origin of these congenital anatomical malformations. Therefore, we examined gene expression patterns in the TEF and compared them ...[more]