Ontology highlight
ABSTRACT:
SUBMITTER: Paquola C
PROVIDER: S-EPMC7671688 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Paquola Casey C Benkarim Oualid O DeKraker Jordan J Larivière Sara S Frässle Stefan S Royer Jessica J Tavakol Shahin S Valk Sofie S Bernasconi Andrea A Bernasconi Neda N Khan Ali A Evans Alan C AC Razi Adeel A Smallwood Jonathan J Bernhardt Boris C BC Bernhardt Boris C BC
eLife 20201104
The mesiotemporal lobe (MTL) is implicated in many cognitive processes, is compromised in numerous brain disorders, and exhibits a gradual cytoarchitectural transition from six-layered parahippocampal isocortex to three-layered hippocampal allocortex. Leveraging an ultra-high-resolution histological reconstruction of a human brain, our study showed that the dominant axis of MTL cytoarchitectural differentiation follows the iso-to-allocortical transition and depth-specific variations in neuronal ...[more]