Ontology highlight
ABSTRACT:
SUBMITTER: Kamino K
PROVIDER: S-EPMC7673753 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Kamino K K Keegstra J M JM Long J J Emonet T T Shimizu T S TS
Science advances 20201113 46
In the face of uncertainty, cell populations tend to diversify to enhance survival and growth. Previous studies established that cells can optimize such bet hedging upon environmental change by modulating gene expression to adapt both the average and diversity of phenotypes. Here, we demonstrate that cells can tune phenotypic diversity also using posttranslational modifications. In the chemotaxis network of <i>Escherichia coli</i>, we find, for both major chemoreceptors Tar and Tsr, that cell-to ...[more]