Long term visuo-vestibular mismatch in freely behaving mice differentially affects gaze stabilizing reflexes.
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ABSTRACT:
SUBMITTER: Franca de Barros F
PROVIDER: S-EPMC7674424 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
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Long term visuo-vestibular mismatch in freely behaving mice differentially affects gaze stabilizing reflexes.
França de Barros Filipa F Schenberg Louise L Tagliabue Michele M Beraneck Mathieu M
Scientific reports 20201118 1
The vestibulo-ocular reflex (VOR) and the optokinetic reflex (OKR) work synergistically to stabilize gaze in response to head movements. We previously demonstrated that a 14-day visuo-vestibular mismatch (VVM) protocol applied in freely behaving mice decreased the VOR gain. Here, we show for the first time that the OKR gain is also reduced and report on the recovery dynamics of both VOR and OKR after the end of the VVM protocol. Using sinusoidally-modulated stimulations, the decreases in VOR and ...[more]
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