Recent Progress in the Understanding and Engineering of Coenzyme B12-Dependent Glycerol Dehydratase.
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ABSTRACT:
SUBMITTER: Nasir A
PROVIDER: S-EPMC7674605 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Recent Progress in the Understanding and Engineering of Coenzyme B<sub>12</sub>-Dependent Glycerol Dehydratase.
Nasir Abdul A Ashok Somasundar S Shim Jeung Yeop JY Park Sunghoon S Yoo Tae Hyeon TH
Frontiers in bioengineering and biotechnology 20201105
Coenzyme B<sub>12</sub>-dependent glycerol dehydratase (GDHt) catalyzes the dehydration reaction of glycerol in the presence of adenosylcobalamin to yield 3-hydroxypropanal (3-HPA), which can be converted biologically to versatile platform chemicals such as 1,3-propanediol and 3-hydroxypropionic acid. Owing to the increased demand for biofuels, developing biological processes based on glycerol, which is a byproduct of biodiesel production, has attracted considerable attention recently. In this r ...[more]
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