Ontology highlight
ABSTRACT:
SUBMITTER: Pratama DE
PROVIDER: S-EPMC7675532 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
ACS omega 20201106 45
The concept of drug recycle by recovering active pharmaceutical ingredients (APIs) from unused tablets and capsules was demonstrated using acetaminophen, tetracycline HCl, and (<i>R</i>,<i>S</i>)-(±)-ibuprofen as case examples. The recovery process comprised three core unit operations: solid-liquid extraction, filtration, and crystallization. Recovery yields of 58.7 wt %, 73.1 wt %, and 67.6 wt % for acetaminophen, tetracycline HCl, and (<i>R</i>,<i>S</i>)-(±)-ibuprofen were achieved, respective ...[more]