Ontology highlight
ABSTRACT:
SUBMITTER: Ortiz AV
PROVIDER: S-EPMC7676510 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Ortiz Alexander V AV Aziz David D Hestrin Shaul S
Cell reports 20201001 3
Animal behavior is motivated by internal drives, such as thirst and hunger, generated in hypothalamic neurons that project widely to many brain areas. We find that water-restricted mice maintain stable, high-level contrast sensitivity and brief reaction time while performing a visual task, but then abruptly stop and become disengaged. Mice consume a significant amount of water when freely provided in their home cage immediately after the task, indicating that disengagement does not reflect cessa ...[more]