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Personality profiles and meteoropathy intensity: A comparative study between young and older adults.

ABSTRACT: OBJECTIVES:This study's main aims were to investigate the Big Five personality trait heterogeneity of study participants in two age groups and to examine whether these traits' heterogeneity can explain possible individual differences in meteoropathy intensity. METHOD:The sample was comprised of 758 participants divided into two age groups: 378 young adults (18-30 years old) and 380 older adults (60+ years old). The participants filled out online or paper versions of the METEO-Q questionnaire and the Ten Item Personality Inventory (TIPI). RESULTS:A latent profile analysis of the completed inventories showed various personality profiles differ in meteoropathy intensity. However, personality's differentiating effect on meteoropathy was observed only among the young adult group. CONCLUSIONS:Our study's results indicate that there is no one personality trait pattern that fits all individuals regarding sensitivity to weather changes. This issue is especially visible when considering age differences.

SUBMITTER: Rzeszutek M

PROVIDER: S-EPMC7676684 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Personality profiles and meteoropathy intensity: A comparative study between young and older adults.

Rzeszutek Marcin M Oniszczenko Włodzimierz W Zalewska Iwona I Pięta Małgorzata M

PloS one 20201119 11

<h4>Objectives</h4>This study's main aims were to investigate the Big Five personality trait heterogeneity of study participants in two age groups and to examine whether these traits' heterogeneity can explain possible individual differences in meteoropathy intensity.<h4>Method</h4>The sample was comprised of 758 participants divided into two age groups: 378 young adults (18-30 years old) and 380 older adults (60+ years old). The participants filled out online or paper versions of the METEO-Q qu ...[more]

PMID: 33211697

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Project description:This study represents the first attempt to perform a profiling analysis of the intergenerational differences in the microRNAs (miRNAs) of melanocytic neoplasms in young adult and older adult groups. Our comparative miRNA profiling provides a novel characterization of the miRnomes of melanocytic neoplasms and melanomas of different age groups and identifies a set of potential diagnostic and potential clinico-pathologic biomarkers that may serve as targets for development of novel miR-based modalities in cancer diagnosis and treatment. An exploratory miRNA analysis of 666 miRs was conducted on formalin fixed and paraffin embedded tissues from 10 adults and 10 young adults including conventional melanoma and melanocytic neoplasms of uncertain biological significance. Age-matched benign melanocytic nevi were used as controls. The comparative profiling was intentionally performed at two extremes of age, i.e., less than 30 years (Mel 30) and greater than 60 years (Mel 60). Primary melanoma in patients greater than 60 years old was characterized by the increased expression of miRs regulating TLR-MyD88-NF-kappaB pathway (hsa-miR -199a), RAS/RAB22A pathway (hsa-miR-204); growth differentiation and migration (hsa-miR337), epithelial mesenchymal transition EMT (let-7b, hsa-miR-10b/10bSTAR(*)), invasion and metastasis (hsa-miR-10b/10bSTAR(*), hsa-miR-30a/e*, hsa-miR-29c*; cellular matrix components (hsa-miR-29c*); invasion-cytokinesis (hsa-miR 99b*) compared to melanoma of younger patients. miR 211 was dramatically downregulated in primary melanoma compared to nevi controls, decreased with increasing age and was among the miRs linked to metastatic processes and potentially targeting the inflammatory receptor CCR10; Primary melanoma in young adult patients was characterized by the increased expression of hsa-miR-449a and decreased expression of hsa-miR146b, hsa-miR 214*. Among the miRs expressed at higher levels in control nevi, compared to adult or young adult melanoma, was hsa-miR 574-3p. Only 2 miRs distinguished adult from young adult-pediatric nevi, hsa-miR374a* and has-miR-566. MiR 30a* appeared to be a strong marker of differentiation in clinical stages I-II adult and pediatric melanoma, and could predict classification of melanoma tissue in the two age groups. Furthermore, lymph node status in the two age groups was characterized by the statistically significant expression of hsa-miR-30a* and hsa-miR-204 (F-test, p-value <0.001).

Dataset Information

Personality profiles and meteoropathy intensity: A comparative study between young and older adults.

Publications

Personality profiles and meteoropathy intensity: A comparative study between young and older adults.

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