Ontology highlight
ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC7677403 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Chen Miaoqin M Hu Shiman S Li Yiling Y Jiang Ting Ting TT Jin Hongchuan H Feng Lifeng L
Signal transduction and targeted therapy 20201120 1
Cancer immunotherapy especially immune checkpoint inhibition has achieved unprecedented successes in cancer treatment. However, there are many patients who failed to benefit from these therapies, highlighting the need for new combinations to increase the clinical efficacy of immune checkpoint inhibitors. In this review, we summarized the latest discoveries on the combination of nucleic acid-sensing immunity and immune checkpoint inhibitors in cancer immunotherapy. Given the critical role of nucl ...[more]