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Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla OXA-244 in Germany, 2019 to 2020.


ABSTRACT: The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.

SUBMITTER: Welker S 

PROVIDER: S-EPMC7678038 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Emergence of carbapenem-resistant ST131 <i>Escherichia coli</i> carrying <i>bla</i><sub>OXA-244</sub> in Germany, 2019 to 2020.

Welker Sybille S   Boutin Sébastien S   Miethke Thomas T   Heeg Klaus K   Nurjadi Dennis D  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20201101 46


The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 <i>Escherichia coli</i> in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing <i>E. coli</i> may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 <i>E. coli</i> is of  ...[more]

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