Ontology highlight
ABSTRACT:
SUBMITTER: Kunjantarachot A
PROVIDER: S-EPMC7678182 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Reproductive biology and endocrinology : RB&E 20201120 1
<h4>Background</h4>Etiology of polycystic ovary syndrome (PCOS) is attributed to genetic and environmental factors. One environmental factor is oxidative stress. Paraoxonase 1 (PON1) is an antioxidant high-density lipoprotein-associated enzyme encoded by the PON1 gene. The PON1 gene has been implicated in the risk for PCOS, the influence of which appears to come from single nucleotide variants (SNVs) at multiple genetic loci. However, association study reports have been inconsistent which compel ...[more]