Dataset Information

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea.

ABSTRACT:

Purpose

Obstructive sleep apnea (OSA) is associated with increased risk for stroke, which is known to further impair respiratory functions. However, it is unknown whether the type and severity of respiratory events are linked to stroke or transient ischemic attack (TIA). Thus, we investigate whether the characteristics of individual respiratory events differ between patients experiencing TIA or acute ischemic stroke and matched patients with clinically suspected sleep-disordered breathing.

Methods

Polygraphic data of 77 in-patients with acute ischemic stroke (n?=?49) or TIA (n?=?28) were compared to age, gender, and BMI-matched patients with suspected sleep-disordered breathing and no cerebrovascular disease. Along with conventional diagnostic parameters (e.g., apnea-hypopnea index), durations and severities of individual apneas, hypopneas and desaturations were compared between the groups separately for ischemic stroke and TIA patients.

Results

Stroke and TIA patients had significantly shorter apneas and hypopneas (p?ConclusionStroke patients had different characteristics of respiratory events, i.e., their polygraphic phenotype of OSA differs compared to matched reference patients. The observed differences in polygraphic features might indicate that stroke and TIA patients suffer from OSA phenotype recently associated with increased cardiovascular mortality. Therefore, optimal diagnostics and treatment require routine OSA screening in patients with acute cerebrovascular disease, even without previous suspicion of OSA.

SUBMITTER: Leino A

PROVIDER: S-EPMC7679322 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Publications

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea.

Leino Akseli A Westeren-Punnonen Susanna S Töyräs Juha J Myllymaa Sami S Leppänen Timo T Ylä-Herttuala Salla S Muraja-Murro Anu A Kantanen Anne-Mari AM Autere Jaana J Jäkälä Pekka P Mervaala Esa E Myllymaa Katja K

Sleep & breathing = Schlaf & Atmung 20200114 4

<h4>Purpose</h4>Obstructive sleep apnea (OSA) is associated with increased risk for stroke, which is known to further impair respiratory functions. However, it is unknown whether the type and severity of respiratory events are linked to stroke or transient ischemic attack (TIA). Thus, we investigate whether the characteristics of individual respiratory events differ between patients experiencing TIA or acute ischemic stroke and matched patients with clinically suspected sleep-disordered breathin ...[more]

PMID: 31938989

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Dataset Information

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea.

Purpose

Methods

Results

Publications

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea.

Similar Datasets

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