Ontology highlight
ABSTRACT:
SUBMITTER: Sakamoto Y
PROVIDER: S-EPMC7679404 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sakamoto Yuki Y Sato Mayuko M Sato Yoshikatsu Y Harada Akihito A Suzuki Takamasa T Goto Chieko C Tamura Kentaro K Toyooka Kiminori K Kimura Hiroshi H Ohkawa Yasuyuki Y Hara-Nishimura Ikuko I Takagi Shingo S Matsunaga Sachihiro S
Nature communications 20201120 1
The nuclear lamina plays an important role in the regulation of chromatin organization and gene positioning in animals. CROWDED NUCLEI (CRWN) is a strong candidate for the plant nuclear lamina protein in Arabidopsis thaliana but its biological function was largely unknown. Here, we show that CRWNs localize at the nuclear lamina and build the meshwork structure. Fluorescence in situ hybridization and RNA-seq analyses revealed that CRWNs regulate chromatin distribution and gene expression. More th ...[more]