Ontology highlight
ABSTRACT:
SUBMITTER: Yi N
PROVIDER: S-EPMC7682016 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Yi Nana N Yu Pengcheng P Wu Lijia L Liu Zhaokun Z Guan Jingzhe J Liu Chang C Liu Mingxu M Lu Yixin Y
Veterinary research 20201123 1
Trichinella spiralis serpin-type serine protease inhibitors (TsSPIs) are expressed in adult worms (AW), newborn larvae (NBL) and muscle larvae (ML) of T. spiralis, with the ML stage demonstrating the highest expression level. This study aims to determine TsSPI functions in larval viability and invasion of intestinal epithelial cells in vitro, as well as their development, survival, and fecundity in vivo via RNAi. TsSPI-specific siRNAs and dsRNA were transfected into ML by incubation. The silenci ...[more]