Ontology highlight
ABSTRACT:
SUBMITTER: Feng Y
PROVIDER: S-EPMC7683673 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Feng Yuemei Y Li Guanzhang G Shi Zhongfang Z Yan Xu X Wang Zhiliang Z Jiang Haoyu H Chen Ye Y Li Renpeng R Zhai You Y Chang Yuanhao Y Zhang Wei W Yuan Fang F
Scientific reports 20201123 1
Glioblastoma (GBM) is the most common and malignant cancer of the central nervous system, and radiotherapy is widely applied in GBM treatment; however, the sensitivity to radiotherapy varies in different patients. To solve this clinical dilemma, a radiosensitivity prediction signature was constructed in the present study based on genomic methylation. In total, 1044 primary GBM samples with clinical and methylation microarray data were involved in this study. LASSO-COX, GSVA, Kaplan-Meier surviva ...[more]