Ontology highlight
ABSTRACT:
SUBMITTER: Brevi A
PROVIDER: S-EPMC7683804 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Brevi Arianna A Cogrossi Laura Lucia LL Grazia Giulia G Masciovecchio Desirée D Impellizzieri Daniela D Lacanfora Lucrezia L Grioni Matteo M Bellone Matteo M
Frontiers in immunology 20201110
The interleukin-(IL-)17 family of cytokines is composed of six members named IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F. IL-17A is the prototype of this family, and it was the first to be discovered and targeted in the clinic. IL-17A is essential for modulating the interplay between commensal microbes and epithelial cells at our borders (i.e., skin and mucosae), and yet, for protecting us from microbial invaders, thus preserving mucosal and skin integrity. Interactions between the microb ...[more]