Predictive Value of the BSID-II and the Bayley-III for Early School Age Cognitive Function in Very Preterm Infants.

ABSTRACT: Objective: To compare the predictive validity of the Bayley Scales of Infant Development, Second Edition (BSID-II) and the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) for cognitive function at early school age in very preterm infants.

Methods: Seventy-seven former preterm infants (born <32?weeks gestation and ?2000?g) completed both the BSID-II and the Bayley-III at 2?years corrected age. Children enrolled at hospitals that perform follow-up beyond 2?years had cognitive assessments with the Wechsler Preschool and Primary Scale of Intelligence Fourth Edition (WPPSI-IV). Associations between Bayley and WPPSI scores were assessed using correlation coefficients, linear regression, and Bland-Altman plots.

Results: Thirty-one of 45 eligible children were tested with the WPPSI-IV at 47 ± 11?months. Average BSID-II Mental Development Index (MDI) was 86 ± 19, Bayley-III Cognitive composite score was 101 ± 12 and WPPSI Full Scale IQ (FSIQ) was 96 ± 12. Correlation between MDI and FSIQ was 0.54 (P?P?=?.03). Bayley-III language composite had a modestly stronger correlation with FSIQ than cognitive composite (correlation coefficient 0.39; P?=?.005). Linear regression models also demonstrated that BSID-II was more closely correlated with FSIQ than Bayley-III. This bias was consistent across the full range of scores.

Conclusion: The BSID-II underestimated FSIQ and the Bayley-III overestimated FSIQ. Children at risk for impairment might be missed with the Bayley-III. As the Bayley-4 is introduced, clinicians and researchers should be cautious about interpretation of scores until performance of this new measure is fully understood.

SUBMITTER: Flynn RS 

PROVIDER: S-EPMC7683841 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature