Ontology highlight
ABSTRACT:
SUBMITTER: Baniahmad A
PROVIDER: S-EPMC7686332 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Baniahmad Adalie A Birkner Katharina K Görg Johanna J Loos Julia J Zipp Frauke F Wasser Beatrice B Bittner Stefan S
Scientific reports 20201124 1
Beyond the major role of T cells in the pathogenesis of the autoimmune neuroinflammatory disorder multiple sclerosis (MS), recent studies have highlighted the impact of B cells on pathogenic inflammatory processes. Follicular T helper cells (Tfh) are essential for the promotion of B cell-driven immune responses. However, their role in MS and its murine model, experimental autoimmune encephalomyelitis (EAE), is poorly investigated. A first step to achieving a better understanding of the contribut ...[more]