Ontology highlight
ABSTRACT:
SUBMITTER: Sagar NM
PROVIDER: S-EPMC7686486 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sagar Nidhi M NM Duboc Henri H Kay Gemma L GL Alam Mohammad T MT Wicaksono Alfian N AN Covington James A JA Quince Christopher C Kokkorou Margarita M Svolos Vaios V Palmieri Lola J LJ Gerasimidis Konstantinos K Walters Julian R F JRF Arasaradnam Ramesh P RP
Scientific reports 20201124 1
Bile acid diarrhoea (BAD) is a common disorder resulting from increased loss of bile acids (BAs), overlapping irritable bowel syndrome with diarrhoea (IBS-D). The gut microbiota metabolises primary BAs to secondary BAs, with differing impacts on metabolism and homeostasis. The aim of this study was to profile the microbiome, metabolic products and bile acids in BAD. Patients with BAD diagnosed by SeHCAT testing, were compared with other IBS-D patients, and healthy controls. Faecal 16S ribosomal ...[more]