Ontology highlight
ABSTRACT:
SUBMITTER: Yang Q
PROVIDER: S-EPMC7686959 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Yang Qianru Q Wu Bingchen B Eles James R JR Vazquez Alberto L AL Kozai Takashi D Y TDY Cui X Tracy XT
Advanced biosystems 20200504 6
For brain computer interfaces (BCI), the immune response to implanted electrodes is a major biological cause of device failure. Bioactive coatings such as neural adhesion molecule L1 have been shown to improve the biocompatibility, but are difficult to handle or produce in batches. Here, a synthetic zwitterionic polymer coating, poly(sulfobetaine methacrylate) (PSBMA) is developed for neural implants with the goal of reducing the inflammatory host response. In tests in vitro, the zwitterionic co ...[more]