Polymorphisms in Fc Gamma Receptors and Susceptibility to Malaria in an Endemic Population.
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ABSTRACT:
SUBMITTER: Amiah MA
PROVIDER: S-EPMC7689034 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Polymorphisms in Fc Gamma Receptors and Susceptibility to Malaria in an Endemic Population.
Amiah Mireille Ahou MA Ouattara Amed A Okou David Tea DT N'Guetta Simon-Pierre Assanvo SA Yavo William W
Frontiers in immunology 20201112
Repeated infections by <i>Plasmodium falciparum</i> result in a humoral response that could reduce disease symptoms and prevent the development of clinical malaria. The principal mechanism underlying this humoral response is that immunoglobulin G (IgG) binds directly to the parasites, thus causing their neutralization. However, the action of antibodies alone is not always sufficient to eliminate pathogens from an organism. One key element involved in the recognition of IgG that plays a crucial r ...[more]
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