Ontology highlight
ABSTRACT:
SUBMITTER: Zeinali T
PROVIDER: S-EPMC7689247 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zeinali Tahereh T Karimi Leila L Hosseinahli Nayer N Shanehbandi Dariush D Mansoori Behzad B Mohammadi Ali A Hajiasgharzadeh Khalil K Babaloo Zohreh Z Majidi-Zolbanin Jafar J Baradaran Behzad B
EXCLI journal 20201103
MiR-145 is a tumor suppressor miRNA that its ubiquitously expressed in the body but in numerous types of cancers such as GC, its expression became reduced or sometimes ceased in many subjects. This study aimed at restoring the function of the miR-145 in MKN-45 cells and investigating the function of this miRNA in proliferation, apoptosis, and migration of GC cells. MKN-45 cells were transfected using the PCMV-miR-145 plasmid vector. The MTT, DAPI staining, and wound healing assays were applied t ...[more]