Ontology highlight
ABSTRACT:
SUBMITTER: Lensu S
PROVIDER: S-EPMC7690286 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Lensu Sanna S Pariyani Raghunath R Mäkinen Elina E Yang Baoru B Saleem Wisam W Munukka Eveliina E Lehti Maarit M Driuchina Anastasiia A Lindén Jere J Tiirola Marja M Lahti Leo L Pekkala Satu S
Nutrients 20201022 11
Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope for therapeutic microbes. We have shown that high hepatic fat content associated with low abundance of <i>Faecalibacterium prausnitzii</i> in humans and, further, the administration of <i>F. prausnitzii</i> prevented NAFLD in mice. Here, we aimed at targeting <i>F. prausnitzii</i> by prebiotic xylo-oligosaccharides (XOS) to treat NAFLD. First, the effect of XOS on <i>F. prausn ...[more]