Ontology highlight
ABSTRACT:
SUBMITTER: Eid SA
PROVIDER: S-EPMC7690408 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Eid Stephanie A SA O'Brien Phillipe D PD Hinder Lucy M LM Hayes John M JM Mendelson Faye E FE Zhang Hongyu H Zeng Lixia L Kretzler Katharina K Narayanan Samanthi S Abcouwer Steven F SF Brosius Iii Frank C FC Pennathur Subramaniam S Savelieff Masha G MG Feldman Eva L EL
Biology 20201022 11
Microvascular complications account for the significant morbidity associated with diabetes. Despite tight glycemic control, disease risk remains especially in type 2 diabetes (T2D) patients and no therapy fully prevents nerve, retinal, or renal damage in type 1 diabetes (T1D) or T2D. Therefore, new antidiabetic drug classes are being evaluated for the treatment of microvascular complications. We investigated the effect of empagliflozin (EMPA), an inhibitor of the sodium/glucose cotransporter 2 ( ...[more]