Dataset Information

Outcome of GORE® ACUSEAL graft for brachial-axillary vascular access in chronic haemodialysis patients: Cohort retrospective single-centre study.

ABSTRACT: Background: The aim of this study was to evaluate the midterm results of a brachio-axillary arteriovenous graft (BA-AVG) for the provision of vascular access haemodialysis patients.

Materials and methods: A cohort retrospective consecutive single-centre study of 46 patients undergoing BA-AVG using the Gore Acuseal, from November 2015 to October 2019 was conducted. Data on patient demographics, comorbidities, medical therapy, and complications were collated for the initial endpoints of primary patency, primary assisted patency, and secondary patency. A subgroup analysis included outcomes in patients over 70 years old and events (complications) per AVG per year. Data were subjected to Kaplan-Meier survival estimator with log-rank analysis and test of probability.

Results: The mean age of the cohort was 63.5 years with male predominance (male, n = 27, 59%). A total of 37 (80%) patient procedures were conducted with elective settings as well as on an emergency basis with a 91.3% technical success rate. The most common complication was grade I steal syndrome (8.7%), followed by graft infections (4.3%), median nerve neuropraxia (4.3%), and postoperative bleeding (2%), demonstrating a 0.1 per AVG complication per 2 years. Median primary patency, primary assisted patency, and secondary patency over a mean follow-up period of 28 months was 5.5, 12.5, and 18 months, respectively, with no associated 30-day mortality.

Conclusion: BA-AVG with midterm longevity and low complications may serve as an alternative access type when a suitable site is not identified. The AVG patency rate in the elderly or patients with limited life expectancy is promising. However, more robust data are needed to confirm the benefit of AVG in this cohort.

SUBMITTER: Sayed T

PROVIDER: S-EPMC7691118 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Outcome of GORE® ACUSEAL graft for brachial-axillary vascular access in chronic haemodialysis patients: Cohort retrospective single-centre study.

Sayed Tamer T Montasser Mahmoud M Ashoor Yasser Y Saad Ahmed A

Annals of medicine and surgery (2012) 20201117

<h4>Background</h4>The aim of this study was to evaluate the midterm results of a brachio-axillary arteriovenous graft (BA-AVG) for the provision of vascular access haemodialysis patients.<h4>Materials and methods</h4>A cohort retrospective consecutive single-centre study of 46 patients undergoing BA-AVG using the Gore Acuseal, from November 2015 to October 2019 was conducted. Data on patient demographics, comorbidities, medical therapy, and complications were collated for the initial endpoints ...[more]

PMID: 33294177

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Project description:BACKGROUND:Haemodialysis treatment requires reliable vascular access. Optimal access is provided via functional arteriovenous fistula (fistula), which compared with other forms of vascular access, provides superior long-term patency, requires few interventions, has low thrombosis and infection rates and cost. However, it has been estimated that between 20% and 60% of fistulas never mature sufficiently to enable haemodialysis treatment. Mapping blood vessels using imaging technologies before surgery may identify vessels that are most suitable for fistula creation. OBJECTIVES:We compared the effect of conducting routine radiological imaging evaluation for vascular access creation preoperatively with standard care without routine preoperative vessel imaging on fistula creation and use. SEARCH METHODS:We searched Cochrane Kidney and Transplant's Specialised Register to 14 April 2015 through contact with the Trials' Search Co-ordinator using search terms relevant to this review. SELECTION CRITERIA:We included randomised controlled trials (RCTs) that enrolled adult participants (aged ? 18 years) with chronic or end-stage kidney disease (ESKD) who needed fistulas (both before dialysis and after dialysis initiation) that compared fistula maturation rates relating to use of imaging technologies to map blood vessels before fistula surgery with standard care (no imaging). DATA COLLECTION AND ANALYSIS:Two authors assessed study quality and extracted data. Dichotomous outcomes, including fistula creation, maturation and need for catheters at dialysis initiation, were expressed as risk ratios (RR) with 95% confidence intervals (CI). Continuous outcomes, such as numbers of interventions required to maintain patency, were expressed as mean differences (MD). We used the random-effects model to measure mean effects. MAIN RESULTS:Four studies enrolling 450 participants met our inclusion criteria. Overall risk of bias was judged to be low in one study, unclear in two, and high in one.There was no significant differences in the number of fistulas that were successfully created (4 studies, 433 patients: RR 1.06, 95% CI 0.95 to 1.28; I² = 76%); the number of fistulas that matured at six months (3 studies, 356 participants: RR 1.11, 95% CI 0.98 to 1.25; I² = 0%); number of fistulas that were used successfully for dialysis (2 studies, 286 participants: RR 1.12, 95% CI 0.99 to 1.28; I² = 0%); the number of patients initiating dialysis with a catheter (1 study, 214 patients: RR 0.66, 95% CI 0.42 to 1.04); and in the rate of interventions required to maintain patency (1 study, 70 patients: MD 14.70 interventions/1000 patient-days, 95% CI -7.51 to 36.91) between the use of preoperative imaging technologies compared with standard care (no imaging). AUTHORS' CONCLUSIONS:Based on four small studies, preoperative vessel imaging did not improve fistula outcomes compared with standard care. Adequately powered prospective studies are required to fully answer this question.

Project description:ObjectivesMaintenance of vascular access (VA) patency after percutaneous transluminal angioplasty (PTA) is important and remains a challenge despite VA monitoring and surveillance. The aim of this study was to examine factors affecting the post-PTA arteriovenous access (AVA) patency in patients who have been on close VA monitoring and surveillance for access flow.DesignRetrospective cohort study.SettingA single medical centre in Taiwan.ParticipantsRecords of patients who received chronic haemodialysis between 1 January 2017 and 31 December 2018 were retrospectively reviewed. Patients were divided into two groups (without or with PTA intervention on AVA).Primary and secondary outcomePatients were followed until reintervention PTA, termination or abandoned VA or end of study. In addition to routine monitoring, VA flow surveillance was performed every 3 months for detection of VA dysfunction adhering to Kidney Disease Outcomes Quality Initiative guidelines.ResultsA total of 508 patients were selected for study inclusion (with PTA, n=231; without PTA, n=277). At baseline, variables that differed between groups included malignancy and levels of albumin, uric acid, potassium, phosphorous, high-density lipoprotein, total bilirubin and ferritin (all p<0.05). Significant between-group differences were observed for β-adrenergic blocking agents (with PTA, 49.8%; without PTA, 37.5%; p, 0.007) and ADP inhibitors (with PTA, 23.8%; without PTA, 11.2%; p<0.001). Among patients with PTA, those with acute myocardial infarction, high ferritin level or arteriovenous graft (AVG) had a significantly higher risk of reintervention post-PTA (p<0.05). Dipeptidyl peptidase-4 inhibitors, thiazolidinediones, ADP inhibitors, and warfarin use were predictors of post-PTA patency (p<0.05).ConclusionsAVG access type, acute myocardial infarction, and high ferritin levels are risk factors for re-intervention post-PTA. These findings may be useful in the development of prophylactic strategies for monitoring VA function and tailoring surveillance programs for these dialysis patients.

Dataset Information

Outcome of GORE® ACUSEAL graft for brachial-axillary vascular access in chronic haemodialysis patients: Cohort retrospective single-centre study.

Publications

Outcome of GORE® ACUSEAL graft for brachial-axillary vascular access in chronic haemodialysis patients: Cohort retrospective single-centre study.

Similar Datasets

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