Ontology highlight
ABSTRACT:
SUBMITTER: Aydillo T
PROVIDER: S-EPMC7691380 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Aydillo Teresa T Escalera Alba A Strohmeier Shirin S Aslam Sadaf S Sanchez-Cespedes Javier J Ayllon Juan J Roca-Oporto Cristina C Perez-Romero Pilar P Montejo Miguel M Gavalda Joan J Munoz Patricia P Lopez-Medrano Francisco F Carratala Jordi J Krammer Florian F García-Sastre Adolfo A Cordero Elisa E
Cell reports. Medicine 20201103 8
Hemagglutination-inhibitory antibodies are usually highly strain specific with little effect on infection with drifted or shifted strains. The significance of broadly cross-reactive non-HAI anti-influenza antibodies against conserved domains of virus glycoproteins, such as the hemagglutinin (HA) stalk, is of great interest. We characterize a cohort of 40 H1N1pmd09 influenza-infected patients and identify lower respiratory symptoms (LRSs) as a predictor for development of pneumonia. A binomial lo ...[more]