The Safety and Efficacy of Phage Therapy for Superficial Bacterial Infections: A Systematic Review.

ABSTRACT: Superficial bacterial infections, such as dermatological, burn wound and chronic wound/ulcer infections, place great human and financial burdens on health systems globally and are often complicated by antibiotic resistance. Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with a 100-year history of successful application. Here, we report a systematic review of the safety and efficacy of phage therapy for the treatment of superficial bacterial infections. Three electronic databases were systematically searched for articles that reported primary data about human phage therapy for dermatological, burn wound or chronic wound/ulcer infections secondary to commonly causative bacteria. Two authors independently assessed study eligibility and performed data extractio

SUBMITTER: Steele A 

PROVIDER: S-EPMC7692203 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature