Ontology highlight
ABSTRACT:
SUBMITTER: Isaja L
PROVIDER: S-EPMC7692563 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Isaja Luciana L Mucci Sofía S Vera Jonathan J Rodríguez-Varela María Soledad MS Marazita Mariela M Morris-Hanon Olivia O Videla-Richardson Guillermo Agustín GA Sevlever Gustavo Emilio GE Scassa María Elida ME Romorini Leonardo L
Scientific reports 20201126 1
Human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are self-renewing human pluripotent stem cells (hPSCs) that can differentiate to a wide range of specialized cells. Notably, hPSCs enhance their undifferentiated state and self-renewal properties in hypoxia (5% O<sub>2</sub>). Although thoroughly analyzed, hypoxia implication in hPSCs death is not fully determined. In order to evaluate the effect of chemically mimicked hypoxia on hPSCs cell survival, we analyzed changes in cel ...[more]