Ontology highlight
ABSTRACT:
SUBMITTER: Porcellato I
PROVIDER: S-EPMC7693514 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Porcellato Ilaria I Mecocci Samanta S Mechelli Luca L Cappelli Katia K Brachelente Chiara C Pepe Marco M Orlandi Margherita M Gialletti Rodolfo R Passeri Benedetta B Ferrari Angelo A Modesto Paola P Ghelardi Alessandro A Razzuoli Elisabetta E
Cells 20201027 11
Penile squamous cell carcinomas (SCCs) are common tumors in older horses, with poor prognosis mostly due to local invasion and recurrence. These tumors are thought to be mainly caused by <i>Equus caballus</i> papillomavirus type 2 (EcPV-2). The aim of this study is to characterize the tumor immune environment (TIME) in equine penile tumors. Equine penile epithelial tumors (17 epSCCs; 2 carcinomas <i>in situ</i>, CIS; 1 papilloma, P) were retrospectively selected; immune infiltrate was assessed b ...[more]