Ontology highlight
ABSTRACT:
SUBMITTER: Jadhav A
PROVIDER: S-EPMC7693698 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Jadhav Archana A Zhao Lele L Ledda Alice A Liu Weiwei W Ding Chan C Nair Venugopal V Ferretti Luca L
Viruses 20201102 11
The expression of accessory non-structural proteins V and W in Newcastle disease virus (NDV) infections depends on RNA editing. These proteins are derived from frameshifts of the sequence coding for the P protein via co-transcriptional insertion of one or two guanines in the mRNA. However, a larger number of guanines can be inserted with lower frequencies. We analysed data from deep RNA sequencing of samples from in vitro and in vivo NDV infections to uncover the patterns of mRNA editing in NDV. ...[more]