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Cannabidiol (CBD) as a Promising Anti-Cancer Drug.


ABSTRACT: Recently, cannabinoids, such as cannabidiol (CBD) and ?9 -tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array of organic molecules, including those that are physiologically produced in humans, synthesized in laboratories, and extracted primarily from the Cannabis sativa plant. These organic molecules share similarities in their chemical structures as well as in their protein binding profiles. However, pronounced differences do exist in their mechanisms of action and clinical applications, which will be briefly compared and contrasted in this review. The mechanism of action of CBD and its potential applications in cancer therapy will be the major focus of this review article.

SUBMITTER: Seltzer ES 

PROVIDER: S-EPMC7693730 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Cannabidiol (CBD) as a Promising Anti-Cancer Drug.

Seltzer Emily S ES   Watters Andrea K AK   MacKenzie Danny D   Granat Lauren M LM   Zhang Dong D  

Cancers 20201030 11


Recently, cannabinoids, such as cannabidiol (CBD) and Δ<sup>9</sup> -tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array of organic molecules, including those that are physiologically produced in humans, synthesized in laboratories, and extracted primarily from the <i>Cannabis sativa</i> plant. These organic molecules share similarities in their chemical structures as well as in their protein binding profiles. However, p  ...[more]

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