Ontology highlight
ABSTRACT:
SUBMITTER: Liu PJ
PROVIDER: S-EPMC7693908 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Viruses 20201025 11
The ability to detect and respond to varying oxygen tension is an essential prerequisite to life. Several mechanisms regulate the cellular response to oxygen including the prolyl hydroxylase domain (PHD)/factor inhibiting HIF (FIH)-hypoxia inducible factor (HIF) pathway, cysteamine (2-aminoethanethiol) dioxygenase (ADO) system, and the lysine-specific demethylases (KDM) 5A and KDM6A. Using a systems-based approach we discuss the literature on oxygen sensing pathways in the context of virus repli ...[more]