Ontology highlight
ABSTRACT:
SUBMITTER: Renner W
PROVIDER: S-EPMC7694227 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Renner Wilfried W Kaiser Melanie M Khuen Sebastian S Trummer Olivia O Mangge Harald H Langsenlehner Tanja T
Genes 20201104 11
<h4>Background</h4>Erythropoietin has a pivotal role in erythropoiesis and angiogenesis. A common polymorphism (rs1617640, A > C) in the promoter of the erythropoietin gene (EPO) has been associated with erythropoietin expression and microvascular complications of diabetes. We aimed to analyze the potential role of this polymorphism in the pathogenesis of peripheral arterial disease (PAD).<h4>Methods</h4>EPO genotypes and laboratory markers for erythropoiesis were determined in 945 patients with ...[more]