Ontology highlight
ABSTRACT:
SUBMITTER: Hung CH
PROVIDER: S-EPMC7697791 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Hung Chun-Hao CH Wang Keh-Yang KY Liou Yae-Huei YH Wang Jing-Ping JP Huang Anna Yu-Szu AY Lee Tung-Liang TL Jiang Si-Tse ST Liao Nah-Shih NS Shyu Yu-Chiau YC Shen Che-Kun James CJ
International journal of molecular sciences 20201110 22
Erythroid Krüppel-like factor (EKLF/KLF1) was identified initially as a critical erythroid-specific transcription factor and was later found to be also expressed in other types of hematopoietic cells, including megakaryocytes and several progenitors. In this study, we have examined the regulatory effects of EKLF on hematopoiesis by comparative analysis of E14.5 fetal livers from wild-type and <i>Eklf</i> gene knockout (KO) mouse embryos. Depletion of EKLF expression greatly changes the populatio ...[more]