Ontology highlight
ABSTRACT:
SUBMITTER: Zottel A
PROVIDER: S-EPMC7698225 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Zottel Alja A Šamec Neja N Kump Ana A Raspor Dall'Olio Lucija Raspor LR Pužar Dominkuš Pia P Romih Rok R Hudoklin Samo S Mlakar Jernej J Nikitin Daniil D Sorokin Maxim M Buzdin Anton A Jovčevska Ivana I Komel Radovan R
International journal of molecular sciences 20201111 22
Glioblastoma (GBM), the most common primary brain tumor, is a complex and extremely aggressive disease. Despite recent advances in molecular biology, there is a lack of biomarkers, which would improve GBM's diagnosis, prognosis, and therapy. Here, we analyzed by qPCR the expression levels of a set of miRNAs in GBM and lower-grade glioma human tissue samples and performed a survival analysis <i>in silico</i>. We then determined the expression of same miRNAs and their selected target mRNAs in smal ...[more]