Ontology highlight
ABSTRACT:
SUBMITTER: Sandy Z
PROVIDER: S-EPMC7698331 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sandy Zac Z da Costa Isabelle Cristine IC Schmidt Christine K CK
Biomolecules 20201115 11
Maintenance of genome stability is a crucial priority for any organism. To meet this priority, robust signalling networks exist to facilitate error-free DNA replication and repair. These signalling cascades are subject to various regulatory post-translational modifications that range from simple additions of chemical moieties to the conjugation of ubiquitin-like proteins (UBLs). Interferon Stimulated Gene 15 (ISG15) is one such UBL. While classically thought of as a component of antiviral immuni ...[more]