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The Cytoscape BioGateway App: explorative network building from the BioGateway triple store.


ABSTRACT: Summary: The BioGateway App is a Cytoscape (version 3) plugin designed to provide easy query access to the BioGateway RDF triple store, which contains functional and interaction information for proteins from several curated resources. For explorative network building, we have added a comprehensive dataset with regulatory relationships of mammalian DNA binding transcription factors and their target genes, compiled both from curated resources and from a text mining effort. Query results are visualised using the inherent flexibility of the Cytoscape framework, and network links can be checked against curated database records or against the original publication.

Availability: Install through the Cytoscape application manager or visit www.biogateway.eu for download and tutorial documents.

Supplementary information: Supplementary information is available at Bioinformatics online.

SUBMITTER: Holmas S 

PROVIDER: S-EPMC7703768 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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The Cytoscape BioGateway App: explorative network building from the BioGateway triple store.

Holmås Stian S   Puig Rafel Riudavets RR   Acencio Marcio Luis ML   Mironov Vladimir V   Kuiper Martin M  

Bioinformatics (Oxford, England) 20191109


<h4>Summary</h4>The BioGateway App is a Cytoscape (version 3) plugin designed to provide easy query access to the BioGateway RDF triple store, which contains functional and interaction information for proteins from several curated resources. For explorative network building, we have added a comprehensive dataset with regulatory relationships of mammalian DNA binding transcription factors and their target genes, compiled both from curated resources and from a text mining effort. Query results are  ...[more]

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